Package: immunarch Type: Package Title: Multi-Modal Immune Repertoire Analytics for Immunotherapy and Vaccine Design in R Version: 0.10.3.9002 Authors@R: c( person("Vadim I.", "Nazarov", , "support@immunomind.com", role = c("aut", "cre"), comment = c(ORCID = "0000-0003-3659-2709")), person("Vasily O.", "Tsvetkov", , role = "aut"), person("Aleksandr A.", "Popov", , role = "aut"), person("Ivan", "Balashov", , role = "aut") ) Contact: support@immunomind.com Description: A comprehensive analytics framework for building reproducible pipelines on T-cell and B-cell immune receptor repertoire data. Delivers multi-modal immune profiling (bulk, single-cell, CITE-seq/AbSeq, spatial, immunogenicity data), feature engineering (ML-ready feature tables and matrices), and biomarker discovery workflows (cohort comparisons, longitudinal tracking, repertoire similarity, enrichment). Provides a user-friendly interface to widely used AIRR methods — clonality/diversity, V(D)J usage, similarity, annotation, tracking, and many more. Think Scanpy or Seurat, but for AIRR data, a.k.a. Adaptive Immune Receptor Repertoire, VDJ-seq, RepSeq, or VDJ sequencing data. A successor to our previously published "tcR" R package (Nazarov 2015). License: Apache License (>= 2.0) URL: https://immunomind.github.io/docs/, https://github.com/immunomind/immunarch/, https://immunarch.com/ BugReports: https://github.com/immunomind/immunarch/issues Depends: R (>= 4.2.0), ggplot2 (>= 3.1.0), immundata (>= 0.0.5), patchwork Imports: dplyr, dtplyr (>= 1.0.0), data.table (>= 1.12.6), cli, pheatmap (>= 1.0.12), reshape2 (>= 1.4.2), circlize, airr, Rcpp (>= 1.0), magrittr, methods, scales, rlang, plyr, stringdist, readr, stringr, tibble, tidyselect, tidyr, ape, doParallel, rlist, utils, glue, checkmate, duckplyr (>= 1.1.2), dbplyr, lifecycle, purrr, stats, vctrs, ggthemes, ggsci LinkingTo: Rcpp Suggests: knitr (>= 1.8), roxygen2 (>= 3.0.0), testthat (>= 3.0.0), pkgdown (>= 0.1.0), assertthat, rmarkdown, factoextra (>= 1.0.4), fpc, ggpubr (>= 0.2), ggraph, ggseqlogo, igraph, phangorn, ggalluvial (>= 0.10.0), UpSetR (>= 1.4.0), ggrepel (>= 0.8.0), shiny (>= 1.4.0), shinythemes, quarto, MASS (>= 7.3), Rtsne (>= 0.15) VignetteBuilder: knitr, quarto Encoding: UTF-8 RoxygenNote: 7.3.3 LazyData: true LazyDataCompression: xz Roxygen: list(markdown = TRUE) Config/Needs/website: rmarkdown Config/testthat/edition: 3 Config/pak/sysreqs: libicu-dev libxml2-dev libx11-dev xz-utils Repository: https://immunomind.r-universe.dev Date/Publication: 2025-11-18 12:28:58 UTC RemoteUrl: https://github.com/immunomind/immunarch RemoteRef: HEAD RemoteSha: 274afb21885f5545930f28a65f1ef750f8a5131f NeedsCompilation: yes Packaged: 2026-06-20 08:05:58 UTC; root Author: Vadim I. Nazarov [aut, cre] (ORCID: ), Vasily O. Tsvetkov [aut], Aleksandr A. Popov [aut], Ivan Balashov [aut] Maintainer: Vadim I. Nazarov